TeleHealth/Telemedicine appointments are available for patients LEARN MORE

Are Peptides Worth the Hype?

With new skincare trends constantly hitting the shelves, it’s hard to know what’s truly effective and what’s just a passing fad. One ingredient that’s been making waves is peptides—but what exactly are they, and do they live up to the buzz? In this installment of our Dermatologist’s Take series, we asked Dr. Fricke to weigh in on the science behind peptides in skincare, how they work, and whether they’re a must-have in your daily routine.

 

What are peptides, and how do they work in skincare?

Dr. Fricke: Peptides are short chains of amino acids—the building blocks of proteins like collagen, elastin, and keratin, which are all crucial for maintaining the skin’s structure, strength, and firmness. In skincare, peptides act as messengers, signaling your skin to perform specific functions like producing more collagen or repairing damage. Think of them as gentle nudges to your skin cells, encouraging them to behave like their younger, more resilient selves.

 

What skin concerns can peptides help improve?

Dr. Fricke: Peptides are multitaskers. Here’s what they can help with:

Fine lines and wrinkles: Boost collagen to smooth skin.
Loss of firmness: Improve elasticity and plumpness.
Dullness and uneven texture: Help with cell regeneration for a more radiant look.
Inflammation and redness: Some peptides have calming, anti-inflammatory properties.
Barrier repair: Strengthen the skin’s protective barrier, which is key for hydration and resilience.

 

How do peptides compare to other anti-aging ingredients like retinol or hyaluronic acid?

Dr. Fricke: Each ingredient shines in its own way:

Retinol is a heavy-hitter for cell turnover and collagen production, but it can be irritating.
Hyaluronic acid hydrates the skin by attracting water, making it great for plumping.
Peptides are like the “support staff” that boost your skin’s function from behind the scenes—gentle, versatile, and often well-tolerated.

The best part? You don’t have to choose just one. They work well together, often amplifying each other’s benefits.

 

Are peptides safe for all skin types?

Dr. Fricke: Yes—peptides are generally very well-tolerated, even by sensitive or reactive skin. Because they don’t exfoliate or increase cell turnover like retinol or AHAs, the risk of irritation is low. 

 

When should I start using peptides in my skincare routine? Can I use peptides with other active ingredients like vitamin C or AHAs?

Dr. Fricke: You can start using them in your mid-20s to early 30s as a preventative measure, or later to help restore firmness and reduce signs of aging.

And yes—peptides play well with others. You can use them with:

Vitamin C: for brightening and antioxidant protection.
Hyaluronic acid: for hydration.
AHAs or BHAs: just use peptides afterward to help soothe and repair.
Retinol: peptides can help buffer irritation and boost collagen-building effects.

 

What should I look for when choosing a peptide product?

Dr. Fricke: Here’s your peptide shopping checklist:

Type of peptides: Look for names like palmitoyl pentapeptidecopper peptides, or matrixyl.
Formulation: Serums tend to deliver peptides more effectively than cleansers or moisturizers.
Packaging: Peptides can be delicate—go for airless pumps or opaque containers to preserve potency.
Complementary ingredients: Products that include niacinamide, ceramides, or antioxidants can supercharge the benefits.

 

How would you rate peptides in skincare on the glow-up scale: 0–5?

Dr. Fricke: 4.5/5
They’re not the flashiest ingredient, but they’re effective, gentle, and versatile. Combine them with hydration and sun protection, and you’ve got a powerful anti-aging routine that works quietly but consistently. They’re like the skincare equivalent of a well-balanced diet—essential and supportive for long-term skin health.

If you’re looking to enhance your skin’s overall appearance, incorporating peptides could be a step in the right direction. Of course, every skin type is different—so if you’re curious about what’s right for you, we’re here to help. Book an appointment with us today and get personalized skincare guidance straight from the experts!

 

NEW LOCATION